Takeoff performance is derived from the basic aircraft weight and balance data, modified for operational, commercial and environmental factors. There can be an error of commission or omission at any stage. Errors can have no significant impact on one hand to a catastrophic impact on the other extreme end of the spectrum. Airlines and the manufacturers have addressed the issues and have formulated new policies, SOP’s and enhanced technical modifications to trap the error. Despite the enhancements, the errors continue to reoccur or occur due to a new reason, which was not addressed before. This paper examines humans from the behavioral aspect in error causation and as the last line of defense in the chain of errors. A new aspect for error causation and failure of humans to adhere to checklists, procedures are analyzed. The solution lies in simplistic methods that can help trap errors to prevent erroneous takeoff performance.